Indomethacin + aldesleukin
1 paper3 findings
- 1 lab in 1 country
- Animals1
Outcomes
3Lifespan
no changein mice1
1 study
Lifespan
no changein mice1
Indomethacin + aldesleukin has no effect on lifespan in mice.
“tumor-bearing aged mice treated as above did not have a significantly longer life span than untreated (control) tumor-bearing mice.”
Animalsin erythroleukemia-bearing aged mice
Effectiveness of immunotherapy in aged leukemic mice
Gerontology1 Jan 1995
Immune response
no changein mice1
1 study
Immune response
no changein mice1
Indomethacin + aldesleukin has no effect on immune response in mice.
“Furthermore, indomethacin and/or rIL-2 could not induce NK cell-mediated activity in such mice.”
Animalsin erythroleukemia-bearing aged mice
Effectiveness of immunotherapy in aged leukemic mice
Gerontology1 Jan 1995
NK cell count
no changein mice1
1 study
NK cell count
no changein mice1
Indomethacin + aldesleukin has no effect on NK cell count in mice.
“neither indomethacin alone, rIL-2 alone, nor the combination could further increase the numbers of these cells.”
Animalsin erythroleukemia-bearing aged mice9 days
Effectiveness of immunotherapy in aged leukemic mice
Gerontology1 Jan 1995