Ags compounds

1. Ags compounds activate wnt/β-catenin signalling in mice.

   “AGS exert their effects partially through TERT-dependent activation of the Wnt-β-catenin pathway.”

   Animalsovaryfemales

   Improvement of fertility in female mice by treatment with novel telomerase-increasing compounds

   Reproductive biology and endocrinology : RB&E·7 Apr 2026

More on Wnt/β-catenin signalling

1. Ags compounds increase number of offspring in mice.

   “Consequently, the number of embryos and offspring increased, with all showing normal development and growth.”

   Animalsfemales

   Improvement of fertility in female mice by treatment with novel telomerase-increasing compounds

   Reproductive biology and endocrinology : RB&E·7 Apr 2026

1. Ags compounds activate telomerase and telomere maintenance in mice.

   “In both age groups, treatment with AGS increased TERT mRNA levels and telomerase activity in the mouse ovary”

   Animalsovaryfemales

   Improvement of fertility in female mice by treatment with novel telomerase-increasing compounds

   Reproductive biology and endocrinology : RB&E·7 Apr 2026

More on Telomerase and telomere maintenance