Age at first birth

Exposure

2 papers3 findings

  • 1 lab in 1 country
  • Funders: National Natural Science Foundation of China and 1 more
  • Humans2

Outcomes

1

Cognitive function

upin silico1

1 study
  1. Age at first birth improves cognitive function in silico.

    “later first birth to better cognition”

    In silicofemales

    Associations of reproductive history with cognitive impairment, depression, and anxiety in older women: a cross-sectional analysis of the CLHLS combined with Mendelian randomization

    Archives of physiology and biochemistry23 Jul 2026

Associations

2

Depression

downin silico1

1 study
  1. Age at first birth lowers the risk of depression in silico.

    “later first birth to better cognition and lower depression risk”

    In silicofemales

    Associations of reproductive history with cognitive impairment, depression, and anxiety in older women: a cross-sectional analysis of the CLHLS combined with Mendelian randomization

    Archives of physiology and biochemistry23 Jul 2026

More on Depression

Frailty

downin humans1

1 study
  1. Age at first birth is associated with frailty in humans.

    “genetically predicted later AFB was associated with lower frailty risk and lower PhenoAge and KDM-BA acceleration”

    Humansfemales

    Reproductive behaviors, genetic susceptibility and accelerated aging risk

    npj aging8 Jul 2026

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