Adverse early life factors

Exposure

1 paper2 findings

  • 1 lab in 1 country
  • Funders: National Key Research and Development Program of China and 3 more
  • Humans1

Outcomes

2

Lifespan

downin humans1

1 study
  1. Adverse early life factors shorten lifespan in humans (0.54 years of life loss at the age of 45 and 0.49 years of life loss at the age of 60).

    “as well as an average of 0.54 years of life loss at the age of 45 and 0.49 years of life loss at the age of 60”

    Humansmore than 3 adverse early life factors vs nonen = 197,504

    Association Between Adverse Early Life Factors and Telomere Length in Middle and Late Life

    Innovation in aging10 Aug 2024

Telomere length

downin humans1

1 study
  1. Adverse early life factors decrease telomere length in humans (β = -0.053, 95% CI -0.069 to -0.038, p < .0001).

    “Individuals who experienced more than 3 adverse early life factors had the shortest TL in middle and late life (β = -0.053; 95% CI = -0.069 to -0.038; p < .0001)”

    Humansmore than 3 adverse early life factors vs nonen = 197,504

    Association Between Adverse Early Life Factors and Telomere Length in Middle and Late Life

    Innovation in aging10 Aug 2024

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