Adipose-derived mesenchymal stem cell exosomes
1 paper4 findings
- 1 lab in 1 country
- Funders: Basic and Applied Basic Research Foundation of Guangdong Province and 1 more
- Animals1
Outcomes
4Mitochondrial fission and fusion
upin human cells1
1 study
Mitochondrial fission and fusion
upin human cells1
Adipose-derived mesenchymal stem cell exosomes improve mitochondrial fission and fusion in human cells.
“enhancing the transcription of mitochondrial dynamin-related protein 1 (Drp1), and ultimately restoring mitochondrial dynamics and alleviating senescence in human dermal fibroblasts (HDFs).”
Cellsin human dermal fibroblasts
Biochimica et biophysica acta. Molecular basis of disease6 Feb 2026
SMARCAL1
downin human cells1
1 study
SMARCAL1
downin human cells1
Adipose-derived mesenchymal stem cell exosomes decrease SMARCAL1 in human cells.
“these exosomes suppress the expression of SMARCAL1, a chromatin remodeling protein, thereby enhancing the transcription of mitochondrial dynamin-related protein 1 (Drp1)”
Cellsin human dermal fibroblasts
Biochimica et biophysica acta. Molecular basis of disease6 Feb 2026
Cellular senescence
downin human cells1
1 study
Cellular senescence
downin human cells1
Adipose-derived mesenchymal stem cell exosomes decrease cellular senescence in human cells.
“Subsequent investigations demonstrated that exosomes derived from adipose-derived stem cells can effectively alleviate fibroblast senescence.”
Cellsin human dermal fibroblasts
Biochimica et biophysica acta. Molecular basis of disease6 Feb 2026
Wound healing
upin mice1
1 study
Wound healing
upin mice1
Adipose-derived mesenchymal stem cell exosomes improve wound healing in mice.
“In vivo experiments further demonstrated that exosome administration significantly reduced HDFs senescence and accelerated wound healing in a diabetic mouse model.”
Animalsin a diabetic mouse model
Biochimica et biophysica acta. Molecular basis of disease6 Feb 2026