ADH-1
- 1 lab in 1 country
- Funder: National Natural Science Foundation of China
- Cells1
Outcomes
1Cellular senescence
downin human cells1
1 study
Cellular senescence
downin human cells1
ADH-1 decreases cellular senescence in human cells.
“Notably, N-cadherin knockdown or pharmacological blockade of its homophilic binding using ADH-1 restored migratory dynamics, enhanced traction generation and alleviated senescence-associated phenotypes.”
Cellsin replicatively senescent hMSCs
Journal of cell science16 Jun 2026
Latest
3 in 12 monthsFree Radical Biology & Medicine
ADORA2B/ador-1 is required for multi-system transcriptional adaptation to mild hypoxia and healthspan extension in C. elegans
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Journal of Cell Science
N-cadherin mediates replicative senescence of mesenchymal stem cells via regulation of intercellular adhesion
Experiments in human cellsCellular senescence
bioRxiv
Broad Effects of Activation of Alcohol Dehydrogenase 1 on Healthspan Extension
Preprint: experiments in model organismsInterventions
Current Biology
Increased alcohol dehydrogenase 1 activity promotes longevity
Experiments in wormsInterventions