Acinetobacter junii

Acinetobacter junii extends lifespan in flies.

“A. junii exploits the host response to promote its growth, leading to lifespan extension”

Model organisms

Microbiome-host interactions drive a trade-off between sleep quality and lifespan in Drosophila

bioRxiv (Cold Spring Harbor Laboratory)·26 Dec 2025Preprint

Acinetobacter junii induces sleep fragmentation in flies.

“A. junii induces sleep fragmentation via its metabolite, urocanic acid, through serotonin receptor-dependent dopamine upregulation.”

Model organismsvia urocanic acid and serotonin receptor-dependent dopamine upregulation

Microbiome-host interactions drive a trade-off between sleep quality and lifespan in Drosophila

bioRxiv (Cold Spring Harbor Laboratory)·26 Dec 2025Preprint