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AAV9-SHRXRA

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Animals1

Outcomes

2

Cellular senescence

downin mice1

1 study

  1. AAV9-SHRXRA decreases cellular senescence in mice.

    “in situ injection of AAV9-shRxra into the kidney reduced proteinuria, RTECs senescence and insulin resistance in DKD mice.”

    Animalsin DKD miceAAV9-shRxrakidney

    RXRα/MR signaling promotes diabetic kidney disease by facilitating renal tubular epithelial cells senescence and metabolic reprogramming

    Translational research : the journal of laboratory and clinical medicineOct 17, 2024

More on Cellular senescence

Proteinuria

downin mice1

1 study

  1. AAV9-SHRXRA decreases proteinuria in mice.

    “in situ injection of AAV9-shRxra into the kidney reduced proteinuria, RTECs senescence and insulin resistance in DKD mice.”

    Animalsin DKD miceAAV9-shRxrakidney

    RXRα/MR signaling promotes diabetic kidney disease by facilitating renal tubular epithelial cells senescence and metabolic reprogramming

    Translational research : the journal of laboratory and clinical medicineOct 17, 2024

More on Proteinuria

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