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Aav pgc-1α gene therapy

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Institute of General Medical Sciences and 2 more
  • Animals1

Outcomes

1

Nociceptive behavior chronification

downin mice1

1 study

  1. Aav pgc-1α gene therapy decreases nociceptive behavior chronification in mice.

    “adeno-associated virus-mediated expression of PGC-1α in S1 interneurons ameliorated aging-associated chronification of nociceptive behavior”

    Animalsaging-associated pain chronificationadeno-associated virus-mediated expressionprimary somatosensory cortex interneuron

    Aging-associated decrease of PGC-1α promotes pain chronification

    Aging cell17 May 2024

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