5c
5c has been studied in 1 paper since 2023: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Nov 23, 2023: “Chemically induced revitalization of damaged hepatocytes for regenerative liver repair”.
At a glance
The findings reach mice, none yet in people. 1 lab in 1 country.
None of its findings points the other way.
- 1 lab in 1 country
- Funders: National Key Research and Development Program of China and 3 more
- Animals1
What did studies of 5c find?
4Studies of 5c measured 4 outcomes, among them liver fibrosis, liver function and hepatocyte regeneration.
Liver fibrosis
downin mice1
1 study
Liver fibrosis
downin mice1
5c decreases liver fibrosis in mice (chronic liver injury).
“Systemic administration of 5C in mice with chronic liver injury promoted hepatocyte regeneration, improved liver function, and ameliorated liver fibrosis”
Animalschronic liver injuryliver
Chemically induced revitalization of damaged hepatocytes for regenerative liver repair
iScience
Liver function
upin mice1
1 study
Liver function
upin mice1
5c improves liver function in mice (chronic liver injury).
“Systemic administration of 5C in mice with chronic liver injury promoted hepatocyte regeneration, improved liver function, and ameliorated liver fibrosis”
Animalschronic liver injuryliver
Chemically induced revitalization of damaged hepatocytes for regenerative liver repair
iScience
Hepatocyte regeneration
upin mice1
1 study
Hepatocyte regeneration
upin mice1
5c increases hepatocyte regeneration in mice (chronic liver injury).
“Systemic administration of 5C in mice with chronic liver injury promoted hepatocyte regeneration”
Animalschronic liver injuryliver
Chemically induced revitalization of damaged hepatocytes for regenerative liver repair
iScience
Cellular senescence
downin mouse cells1
1 study
Cellular senescence
downin mouse cells1
5c decreases cellular senescence in mouse cells (damaged hepatocytes from CCl4-induced mice).
“reverse the damage-associated phenotype (e.g., dysfunction, senescence, epithelial to mesenchymal transition, growth arrest, and pro-inflammatory gene expression) in damaged hepatocytes”
Cellsdamaged hepatocytes from CCl4-induced micehepatocytes
Chemically induced revitalization of damaged hepatocytes for regenerative liver repair
iScience