5-bromodeoxyuridine
Across all fields, 2 papers: none in people yet, 1 in animals, 1 in cells
- 1 lab in 1 country
- Animals1
- Cells1
Outcomes
2Cellular senescence
upin reviews1
1 study
Cellular senescence
upin reviews1
5-bromodeoxyuridine induces cellular senescence.
“BrdU effectively induces cellular senescence, a phenomenon of irreversible growth arrest in mammalian cells”
Review
The FEBS journal
Lifespan
downin rats1
1 study
Lifespan
downin rats1
5-bromodeoxyuridine shortens lifespan in rats.
“a dose-dependent shortening of the life span was observed after administration to neonatal animals.”
Animals
Shortening of life span caused by administration of 5-bromodeoxyuridine to neonatal rats
Chemico-biological interactions
Latest
1 paper in 12 monthsNature Communications
Systematic profiling reveals distinct senescence signatures and regulators across human brain cell types
Study in peopleCellular senescence
bioRxiv
Regulatory Network Inference of Induced Senescent Midbrain Cell Types Reveals Cell Type-Specific Senescence-Associated Transcriptional Regulators
Preprint: experiments in human cellsCellular senescence
The FEBS Journal
Nucleosome disruption by 5-bromodeoxyuridine leads to senescence
CommentaryMechanisms
Biochemical and Biophysical Research Communications
Aberrant localization of lamin B receptor (LBR) in cellular senescence in human cells
Experiments in human cellsCellular senescence
Molecular Brain
Reprogramming non-human primate somatic cells into functional neuronal cells by defined factors
Experiments in cellsInterventions
Mechanisms of Ageing and Development
The relationship of DNA excision repair of ultraviolet-induced lesions to the maximum life span of mammals
Experiments in cellsMechanisms
Chemico-biological Interactions
Shortening of life span caused by administration of 5-bromodeoxyuridine to neonatal rats
Experiments in ratsMechanisms