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3-(3,4-dihydroxyphenyl)propionic acid

3-(3,4-dihydroxyphenyl)propionic acid has been studied in 1 paper since 2022: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Jun 12, 2022: “DAF-16 is involved in colonic metabolites of ferulic acid-promoted longevity and stress resistance of Caenorhabditis elegans”.

Intervention

1 paper studies it1 findingUpdated

PubChemChEBI

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Basic and Applied Basic Research Foundation of Guangdong Province and 1 more
  • Model organisms1

What did studies of 3-(3,4-dihydroxyphenyl)propionic acid find?

1

Studies of 3-(3,4-dihydroxyphenyl)propionic acid measured 1 outcome; the most studied are lifespan (1 study).

Lifespan

upin worms1+11% mean lifespan

1 study

  1. 3-(3,4-dihydroxyphenyl)propionic acid extends lifespan in worms (+11.2% mean lifespan).

    “3,4diOHPPA (0.5 mmol L−1 ), 3OHPPA (2.5 mmol L−1 ) and 3PPA (2.5 mmol L−1 ) prolonged the mean lifespan by 11.2%, 13.0% and 10.6%, respectively.”

    Model organisms0.5 mmol L-1

    DAF-16 is involved in colonic metabolites of ferulic acid-promoted longevity and stress resistance of Caenorhabditis elegans

    Journal of the science of food and agriculture

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