AgingResearch.NewsJoin free

2-(3,4-dihydroxyphenyl)ethyl 3-hydroxybutanoate

Intervention

1 paper4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: China Postdoctoral Science Foundation and 5 more
  • Animals1

Outcomes

4

Gut barrier integrity

upin mice1

1 study

  1. 2-(3,4-dihydroxyphenyl)ethyl 3-hydroxybutanoate improves gut barrier integrity in mice.

    “HTHB treatment exhibited an enhancement of gut barrier integrity in colon tissue in SAMP8 mice”

    Animalsin colon tissue in SAMP8 micecolon

    2-(3,4-Dihydroxyphenyl)ethyl 3-hydroxybutanoate Ameliorates Cognitive Dysfunction and Inflammation Via Modulating Gut Microbiota in Aged Senescence-Accelerated Mouse Prone8 Mice

    The journals of gerontology. Series A, Biological sciences and medical sciences1 Sep 2024

Lymphocyte aberrance

downin mice1

1 study

  1. 2-(3,4-dihydroxyphenyl)ethyl 3-hydroxybutanoate decreases lymphocyte aberrance in mice.

    “HTHB mitigated memory decline and lymphocyte aberrance”

    Animalsin senescence-accelerated mouse prone 8 mice

    2-(3,4-Dihydroxyphenyl)ethyl 3-hydroxybutanoate Ameliorates Cognitive Dysfunction and Inflammation Via Modulating Gut Microbiota in Aged Senescence-Accelerated Mouse Prone8 Mice

    The journals of gerontology. Series A, Biological sciences and medical sciences1 Sep 2024

Inflammation

downin mice1

1 study

  1. 2-(3,4-dihydroxyphenyl)ethyl 3-hydroxybutanoate decreases inflammation in mice.

    “reduced inflammation in the brain cortex, intestine and peripheral system”

    Animalsin senescence-accelerated mouse prone 8 mice

    2-(3,4-Dihydroxyphenyl)ethyl 3-hydroxybutanoate Ameliorates Cognitive Dysfunction and Inflammation Via Modulating Gut Microbiota in Aged Senescence-Accelerated Mouse Prone8 Mice

    The journals of gerontology. Series A, Biological sciences and medical sciences1 Sep 2024

More on Inflammation

Memory decline

downin mice1

1 study

  1. 2-(3,4-dihydroxyphenyl)ethyl 3-hydroxybutanoate decreases memory decline in mice.

    “Results revealed that HTHB mitigated memory decline”

    Animalsin senescence-accelerated mouse prone 8 mice

    2-(3,4-Dihydroxyphenyl)ethyl 3-hydroxybutanoate Ameliorates Cognitive Dysfunction and Inflammation Via Modulating Gut Microbiota in Aged Senescence-Accelerated Mouse Prone8 Mice

    The journals of gerontology. Series A, Biological sciences and medical sciences1 Sep 2024

Latest

Related