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1-methylxanthine, 3-methylxanthine, paraxanthine, and ceramide

Exposure

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Natural Science Foundation of China and 1 more
  • Human trial1

Outcomes

1

Senescent CD4+CD57+ T-cell frequency

downin cells1

1 study

  1. 1-methylxanthine, 3-methylxanthine, paraxanthine, and ceramide decreases Senescent CD4+CD57+ T-cell frequency in cells.

    “coffee-associated metabolites, such as 1-methylxanthine, 3-methylxanthine, paraxanthine, and ceramide, reduced the frequency of senescent CD4+CD57+T cells in vitro.”

    CellsIn vitroT cells

    Metabolic shifts during coffee consumption refresh the immune response: insight from comprehensive multiomics analysis

    MedComm17 Jun 2024

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