zfp-1

Gene

1 paper2 findings

Taxon 6239

  • 1 lab in 1 country
  • Funders: Anatomical Society and 5 more
  • Model organisms1

Effects

2

Gene expression

downin worms1

1 study
  1. zfp-1 decreases gene expression in worms.

    “ZFP-1, in turn, negatively regulates the expression of DAF-16/FOXO and PHA-4/FOXA target genes”

    Model organisms

    A chromatin modifier integrates insulin/IGF-1 signalling and dietary restriction to regulate longevity

    Aging cell2 Apr 2016

Lifespan

is required forin worms1

1 study
  1. zfp-1 is required for lifespan in worms.

    “Consequently, zfp-1 is required for the enhanced longevity observed during DR and on knockdown of IIS.”

    Model organismsduring DR

    A chromatin modifier integrates insulin/IGF-1 signalling and dietary restriction to regulate longevity

    Aging cell2 Apr 2016

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