USP2

Gene1 paper3 findings

Animals1

Effects

3

CD274

upin mice1

1 study

USP2 increases CD274 in mice.
Animals
USP2 safeguards retinal homeostasis by stabilizing macrophage PD-L1 to restrain CD8⁺ T cell cytotoxicity in age-related macular degeneration · Research Square · 17 Sep 2026 · Preprint

RPE damage

downin mice1

1 study

USP2 decreases RPE damage in mice.
Animalsfollowing oxidative injury
USP2 safeguards retinal homeostasis by stabilizing macrophage PD-L1 to restrain CD8⁺ T cell cytotoxicity in age-related macular degeneration · Research Square · 17 Sep 2026 · Preprint

Retinal degeneration

downin mice1

1 study

USP2 decreases retinal degeneration in mice.
Animalsfollowing oxidative injury
USP2 safeguards retinal homeostasis by stabilizing macrophage PD-L1 to restrain CD8⁺ T cell cytotoxicity in age-related macular degeneration · Research Square · 17 Sep 2026 · Preprint

Latest

1

Research SquareAnimalsPreprint18 Sep

USP2 safeguards retinal homeostasis by stabilizing macrophage PD-L1 to restrain CD8⁺ T cell cytotoxicity in age-related macular degeneration