What does the research say about TRAF1?

TRAF1

There are 3 papers on TRAF1 in aging research: none in people yet, 2 in animals. The newest story, Nov 13, 2026: “Lowering a protein improved heart relaxation in aged mice”.

Gene

3 papers study it1 finding

HGNC NCBI Gene Taxon

1 new paper in 30 daysSee all 3 papers on TRAF1

At a glance

The findings reach cells, none yet in people. 1 lab.

1 lab

Animals2
In silico1

Effects

cardiomyocyte senescence

upin mouse cells1

1 study

TRAF1 increases cardiomyocyte senescence in mouse cells (D-galactose treatment; shown by knockdown and overexpression).
“TRAF1 knockdown attenuated D-gal-induced cardiomyocyte senescence and ROS accumulation, whereas overexpression exacerbated these changes.”
CellsD-galactose treatment; shown by knockdown and overexpressionprimary cardiomyocytes
Lowering a protein improved heart relaxation in aged mice
Cell biology and toxicologyNov 13, 2026

Latest

2 papers in 12 months

Cell Biology and ToxicologyNov 13

Lowering a protein improved heart relaxation in aged mice

Mice given a heart-cell-targeted gene-silencing injection at 90 weeks had less inflammation and better heart relaxation when assessed at 110 weeks.Mice given a heart-cell-targeted gene-silencing injection at 90 weeks had less inflammation and better heart relaxation when assessed at 110 weeks.

Mouse studyMechanisms