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TFPI

There are 7 papers on TFPI in aging research: 1 trial and 5 observational studies in people, 1 in animals. The newest story, Oct 26, 2026: “Protein linked to risk after acute coronary syndrome in older patients”.

Gene

7 papers study it1 finding

HGNCNCBI GeneTaxon

2 new papers in 30 daysSee all 7 papers on TFPI

At a glance

The findings reach mice, none yet in people. 1 lab in 1 country.

Mice: a single group. Cells, worms or flies and humans: nothing yet.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funder: Japan Society for the Promotion of Science
  • Human trial1
  • Humans5
  • Animals1

Upstream

1

Hypertension

downin rats1

1 study

  1. Hypertension decreases TFPI in rats (spontaneously hypertensive rats).

    “In contrast, in SHR rats, only the TFPI expression has significantly decreased, while TM was preserved to the same level of control 30-week-old WKY rats.”

    Animalsspontaneously hypertensive ratsatrial endocardium

    Effects of Aging and Hypertension on the Antithrombotic Function of Atrial Endocardium in Rats

    International heart journal

More on Hypertension

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 1Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 2Nov 2026: 03 papers in 12 months
ESC Congress 2026 Abstract

Protein linked to risk after acute coronary syndrome in older patients

Among patients aged 55 or older with acute coronary syndrome, each protein doubling was linked to higher one-year cardiovascular risk (adjusted hazard ratio 1.28).Among patients aged 55 or older with acute coronary syndrome, each protein doubling was linked to higher one-year cardiovascular risk (adjusted hazard ratio 1.28).

Cohort · 4,787 peopleMechanisms
Paper
Clinical Cancer Research

Blood test panel better distinguished pancreatic cancer cases

The leading panel scored 96.3 versus 91.7 for a single blood marker on a measure of how well tests separated cancer cases from controls.The leading panel scored 96.3 versus 91.7 for a single blood marker on a measure of how well tests separated cancer cases from controls.

Case-control · 280 peoplePancreatic ductal adenocarcinoma
Paper

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