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TELOMERE-RELATEDGENES

Gene

1 paper studies it2 findings

Effects

1

Forced vital capacity

downin humans1

1 study

  1. TELOMERE-RELATEDGENES impairs forced vital capacity in humans.

    “presence of TRG mutation may also be associated with an accelerated decline of forced vital capacity (FVC)”

    Reviewin ILD patients

    Telomeres and lung

    Revue des maladies respiratoires

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Associations

1

Interstitial lung disease

upin humans1+30%

1 study

  1. TELOMERE-RELATEDGENES is associated with interstitial lung disease in humans (approximately 30%).

    “discovery of telomere-related gene (TRG) mutations (TERT, TERC, RTEL1, PARN, DKC1, TINF2, NAF1, NOP10, NHP2, ACD, ZCCH8) in approximately 30% of familial ILD forms”

    Reviewin familial interstitial lung disease

    Telomeres and lung

    Revue des maladies respiratoires

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