AgingResearch.NewsJoin free

TBC1D30

Gene

1 paper2 findings

HGNCNCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Hungarian Scientific Research Fund and 1 more
  • Model organisms1

Effects

2

Active Rab2 protein

downin human cells1

1 study

  1. TBC1D30 decreases active Rab2 protein in human cells.

    “Silencing TBC1D30 increased the number of active Rab2 protein and enhanced autophagic activity in human cells.”

    CellsShown by TBC1D30 silencingHeLa

    The GTPase-activating protein CG42795 is a potent neuronal regulator of ageing in Drosophila melanogaster

    bioRxiv (Cold Spring Harbor Laboratory)19 Jun 2024Preprint

More on Active Rab2 protein

Autophagy

downin human cells1

1 study

  1. TBC1D30 inhibits autophagy in human cells.

    “Silencing TBC1D30 increased the number of active Rab2 protein and enhanced autophagic activity in human cells.”

    CellsShown by TBC1D30 silencingHeLa

    The GTPase-activating protein CG42795 is a potent neuronal regulator of ageing in Drosophila melanogaster

    bioRxiv (Cold Spring Harbor Laboratory)19 Jun 2024Preprint

More on Autophagy

Latest

Related