SUV3

1 paper2 findings

HGNC NCBI Gene Taxon

1 lab in 2 countries

Funders: National Institute of Diabetes and Digestive and Kidney Diseases and 3 more

Animals1

Effects

2

Lifespan

upin mice1

1 study

SUV3 extends lifespan in mice.
“mSuv3+/- mice harbored increased mitochondrial DNA (mtDNA) mutations and decreased mtDNA copy numbers, leading to tumor development in various sites and shortened lifespan.”
Animalshaploinsufficiency / mSuv3+/-
Mitochondrial genome instability resulting from SUV3 haploinsufficiency leads to tumorigenesis and shortened lifespan
Oncogene7 May 2012

Tumor development

downin mice1

1 study

SUV3 prevents tumor development in mice.
“mSuv3+/- mice harbored increased mitochondrial DNA (mtDNA) mutations and decreased mtDNA copy numbers, leading to tumor development in various sites and shortened lifespan.”
Animalshaploinsufficiency / mSuv3+/-
Mitochondrial genome instability resulting from SUV3 haploinsufficiency leads to tumorigenesis and shortened lifespan
Oncogene7 May 2012

More on Tumor development

Latest

Oncogene7 May

Mitochondrial genome instability resulting from SUV3 haploinsufficiency leads to tumorigenesis and shortened lifespan

Experiments in miceMitochondrion