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spp-1

Gene

3 papers study it2 findings

NCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Institutes of Health and 1 more
  • Model organisms3

Effects

2

Ectopic induction of P3.p vulval precursor cell

downin worms1

1 study

  1. spp-1 inhibits ectopic induction of P3.p vulval precursor cell in worms.

    “In all cases, the ectopic induction of P3.p vulval precursor cell was also inhibited.”

    Model organismsin pry-1 mutants via RNA interference

    Genetic analysis of Caenorhabditis elegans pry-1/Axin suppressors identifies genes involved in reproductive structure development, stress responses, and aging

    G3 (Bethesda, Md.)

Multivulva phenotype

downin worms1

1 study

  1. spp-1 decreases multivulva phenotype in worms.

    “Knocking down eight of the genes (spp-1, clsp-1, ard-1, rpn-7, cpz-1, his-7, cdk-1, and rnr-1) via RNA interference efficiently suppressed the multivulva phenotype of pry-1 mutants.”

    Model organismsin pry-1 mutants via RNA interference

    Genetic analysis of Caenorhabditis elegans pry-1/Axin suppressors identifies genes involved in reproductive structure development, stress responses, and aging

    G3 (Bethesda, Md.)

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