AgingResearch.NewsJoin free

spo

Gene

1 paper3 findings

NCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Model organisms1

Effects

3

Basal activity

no changein flies1

1 study

  1. spo has no effect on basal activity in flies.

    “without affecting basal activity”

    Model organisms

    spook haploinsufficiency exacerbates aging-related motor impairments

    microPublication biology15 Oct 2025

Ecdysone

downin flies1

1 study

  1. spo decreases ecdysone in flies.

    “spook heterozygous flies with reduced brain ecdysone exhibit accelerated, aging-related declines in climbing performance”

    Model organismsspook heterozygositybrain

    spook haploinsufficiency exacerbates aging-related motor impairments

    microPublication biology15 Oct 2025

More on Ecdysone

Climbing performance

downin flies1

1 study

  1. spo impairs climbing performance in flies.

    “spook heterozygous flies with reduced brain ecdysone exhibit accelerated, aging-related declines in climbing performance”

    Model organismshaploinsufficiencybrain

    spook haploinsufficiency exacerbates aging-related motor impairments

    microPublication biology15 Oct 2025

Latest

Related