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SNELLDWARF

Gene

1 paper studies it3 findings

None of its findings points the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Institute of Diabetes and Digestive and Kidney Diseases and 5 more
  • Animals1

Effects

2

Secretogranin II

upin mice1

1 study

  1. SNELLDWARF increases Secretogranin II in mice.

    “Radioimmune assays confirmed that circulating Chromogranin B and Secretogranin II were elevated in 12 to 14 month-old Snell dwarf mice.”

    Animals

    Neuroendocrine inhibition of glucose production and resistance to cancer in dwarf mice

    Experimental gerontology

More on Secretogranin II

Chromogranin B

upin mice1

1 study

  1. SNELLDWARF increases Chromogranin B in mice.

    “Radioimmune assays confirmed that circulating Chromogranin B and Secretogranin II were elevated in 12 to 14 month-old Snell dwarf mice.”

    Animals

    Neuroendocrine inhibition of glucose production and resistance to cancer in dwarf mice

    Experimental gerontology

More on Chromogranin B

Associations

1

Cancer incidence

downin mice1

1 study

  1. SNELLDWARF lowers the risk of cancer incidence in mice (18% vs 82%).

    “Only 18% of old Snell dwarf mice had malignant lesions at the time of death compared to 82% of control mice.”

    Animalsat the time of death

    Neuroendocrine inhibition of glucose production and resistance to cancer in dwarf mice

    Experimental gerontology

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