SEN1

Gene

1 paper studies it1 finding

Taxon

  • 1 lab in 1 country
  • Funders: Deutsche Forschungsgemeinschaft and 1 more
  • Cells1

Effects

1

Cellular senescence

downin yeast cells1

1 study
  1. SEN1 prevents cellular senescence in yeast cells.

    “In the absence of RNase H1 or Sen1 function, yeast cultures prematurely enter replicative senescence in the absence of telomerase.”

    Cellsin the absence of telomerase

    RNase H1 and Sen1 ensure that transient TERRA R-loops promote the repair of short telomeres

    EMBO reports

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