SEB

Gene

1 paper3 findings

HGNCNCBI GeneTaxon

  • 1 lab in 1 country
  • Animals1

Effects

1

Lifespan

no changein mice1

1 study
  1. SEB has no effect on lifespan in mice.

    “Life expectancy was not affected significantly by genotype.”

    Animalshomozygous seb vs heterozygous littermates

    Reduced tumour incidence in mice with inherited seborrhoeic dermatitis

    Laboratory animals1 Oct 1994

Associations

2

Epithelial tumours of the skin

upin mice1

1 study
  1. SEB raises the risk of epithelial tumours of the skin in mice.

    “skin tumours were detected in 11 homozygous but only in one heterozygous animal.”

    Animalshomozygous seb vs heterozygous littermates

    Reduced tumour incidence in mice with inherited seborrhoeic dermatitis

    Laboratory animals1 Oct 1994

More on Epithelial tumours of the skin

Tumours

downin mice1

1 study
  1. SEB lowers the risk of tumours in mice (36.1% vs 84.1%).

    “Heterozygotes showed 84.1% total tumour incidence in males and 95.9% in females.”

    Animalshomozygous seb vs heterozygous littermatesmales

    Reduced tumour incidence in mice with inherited seborrhoeic dermatitis

    Laboratory animals1 Oct 1994

More on Tumours

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