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SCN1A

Gene

1 paper studies it1 finding

HGNCNCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

No results posted: trials that ended over a year ago with no results on ClinicalTrials.gov and no paper reporting them.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • 2 trials, 1 with no results posted
  • Funders: Guangzhou Municipal Science and Technology Bureau and 2 more
  • 2 of 2 trials sponsored by developers of drugs on it
  • Animals1

Effects

1

Plasma membrane depolarization

mediatesin mouse cells1

1 study

  1. SCN1A mediates plasma membrane depolarization in mouse cells.

    “We further identified the sodium channel Scn1a as a mediator of membrane depolarization in senescent preosteoblasts.”

    Cellsin senescent preosteoblastspreosteoblast

    mTORC1 induces plasma membrane depolarization and promotes preosteoblast senescence by regulating the sodium channel Scn1a

    Bone research

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