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SARS1

Gene

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Agence Nationale de la Recherche and 5 more
  • Humans1

Effects

2

Cellular senescence

upin human cells1

1 study

  1. SARS1 induces cellular senescence in human cells.

    “Fibroblasts showed an abnormal cell shape, arrested division and increased beta-galactosidase staining along with a senescence-associated secretory phenotype”

    Cellsde novo splice site deletion in SARS1fibroblasts

    Loss of seryl-tRNA synthetase (SARS1) causes complex spastic paraplegia and cellular senescence

    Journal of medical geneticsAug 30, 2022

More on Cellular senescence

Spastic paraplegia

upin humans1

1 study

  1. SARS1 induces spastic paraplegia in humans.

    “Loss of seryl-tRNA synthetase (SARS1) causes complex spastic paraplegia and cellular senescence”

    Humansde novo splice site deletion in SARS1

    Loss of seryl-tRNA synthetase (SARS1) causes complex spastic paraplegia and cellular senescence

    Journal of medical geneticsAug 30, 2022

More on Spastic paraplegia

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