RS1800628
1 paper2 findings
- 1 lab in 1 country
- Humans1
Associations
2Systemic immune remodeling
mixedin humans1
1 study
Systemic immune remodeling
mixedin humans1
RS1800628 is associated with systemic immune remodeling in humans.
“the signal variation is associated with systemic immune remodeling, characterized by increased pro-inflammatory mediators, elevated T-cell regulation markers, and reduced lymphocyte counts.”
Humansphenome-wide association and network analyses
medRxiv29 Apr 2026Preprint
Shared genetic signal across mvAge, rheumatoid arthritis, and herpes zoster
mixedin humans1
1 study
Shared genetic signal across mvAge, rheumatoid arthritis, and herpes zoster
mixedin humans1
RS1800628 is associated with shared genetic signal across mvAge, rheumatoid arthritis, and herpes zoster in humans.
“we identified a shared pleiotropic major histocompatibility complex (MHC) signal, tagged by rs1800628”
HumansGWAS integration, colocalization, and Mendelian randomization
medRxiv29 Apr 2026Preprint
Latest
1 in 12 monthsmedRxiv
A shared MHC immunogenetic signal connects aging, rheumatoid arthritis, and herpes zoster through chronic high inflammatory burden–compensatory immune tolerance dysregulation
Preprint: Mendelian randomisation in peopleImmune response