RAP1A
Gene2 papers5 findings
- Animals2
Effects
4Cellular senescence
is required forin cells1
1 study
Cellular senescence
is required forin cells1
RAP1A is required for cellular senescence in cells.
Cellsin MTR4-driven VSMC senescence
MTR4 deficiency attenuates abdominal aortic aneurysm progression through suppressing VSMC senescence via the MTR4-RAP1a axis · iScience · 9 Sep 2026
Heart weight
upin mice1
1 study
Heart weight
upin mice1
RAP1A increases heart weight in mice.
Animalsheartmales
Distinct Effects of Rap1 Subtype A GTPase Deficiency on the Male Mouse Heart · Cells · 4 Sep 2026
Collagen type III
upin mice1
1 study
Collagen type III
upin mice1
RAP1A increases collagen type III in mice.
Animalsbaseline and cardiovascular stress conditionsheartmales
Distinct Effects of Rap1 Subtype A GTPase Deficiency on the Male Mouse Heart · Cells · 4 Sep 2026
Collagen type I
upin mice1
1 study
Collagen type I
upin mice1
RAP1A increases collagen type I in mice.
Animalsbaseline and cardiovascular stress conditionsheartmales
Distinct Effects of Rap1 Subtype A GTPase Deficiency on the Male Mouse Heart · Cells · 4 Sep 2026
Associations
1Mortality
downin mice1
1 study
Mortality
downin mice1
RAP1A lowers the risk of mortality in mice.
Animalsupon cardiac stressmales
Distinct Effects of Rap1 Subtype A GTPase Deficiency on the Male Mouse Heart · Cells · 4 Sep 2026
Funding
National Heart, Lung, and Blood InstituteUS$632.9k1 grant since 2023