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ptr-8

Gene

1 paper2 findings

Taxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Key Research and Development Program of China and 1 more
  • Model organisms1

Effects

2

Proteostasis

downin worms1

1 study

  1. ptr-8 impairs proteostasis in worms.

    “elevated expression of PTR-8/Patched is responsible for the proteostasis and lifespan defects of acs-20.”

    Model organismsin acs-20 mutants

    ACS-20/FATP4 mediates the anti-ageing effect of dietary restriction in C. elegans

    Nature communicationsNov 24, 2023

More on Proteostasis

Lifespan

downin worms1

1 study

  1. ptr-8 shortens lifespan in worms.

    “elevated expression of PTR-8/Patched is responsible for the proteostasis and lifespan defects of acs-20.”

    Model organismsin acs-20 mutants

    ACS-20/FATP4 mediates the anti-ageing effect of dietary restriction in C. elegans

    Nature communicationsNov 24, 2023

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