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POP5

Gene

1 paper studies it1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 3 countries
  • Funders: American Asthma Foundation and others
  • 1 of 1 finding with company ties
  • Humans1

Effects

1

Telomere length

upin human cells1

1 study

  1. POP5 increases telomere length in human cells.

    “overexpressing KBTBD6 , a component of an E3 ubiquitin ligase complex, and POP5 , a component of the Ribonuclease P/MRP complex, and demonstrating that both lengthened telomeres”

    Cellsoverexpression

    Validation of human telomere length trans-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as novel human telomere length regulation genes

    bioRxiv (Cold Spring Harbor Laboratory)Preprint

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