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pgrn-1

Gene

1 paper1 finding

NCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Institute of General Medical Sciences and 3 more
  • Model organisms1

Effects

1

Lifespan

no changein worms1

1 study

  1. pgrn-1 has no effect on lifespan in worms.

    “Lowering the expression of pgrn-1 and flp genes selectively in neural tissue showed no difference in survival under normal feeding conditions nor under DR”

    Model organismsin neural tissue under normal feeding or DRneural tissue

    Roles of progranulin and FRamides in neural versus non-neural tissues on dietary restriction-related longevity and proteostasis in C. elegans

    bioRxiv : the preprint server for biology8 Feb 2024Preprint

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