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PDAP1

Gene

1 paper studies it2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Common Fund and others
  • Humans1

Effects

2

Cellular senescence

upin human cells1

1 study

  1. PDAP1 increases cellular senescence in human cells.

    “the deficiency of PDAP1 attenuates replicative senescence.”

    Cellsdeficiency / knockdown

    Identifying PDAP1 as a Biological Target on Human Longevity: Integration of Mendelian Randomization, Cohort, and Cell Experiments Validation Study

    Aging cellApr 10, 2025

More on Cellular senescence

Longevity

downin silico1

1 study

  1. PDAP1 decreases longevity in silico.

    “a cascading effect of both the tissue-specific transcripts and plasma proteins of LPA, PDAP1, DNAJA4, and TMEM106B showed negative effects on longevity.”

    In silicocascading effect of tissue-specific transcripts and plasma proteins

    Identifying PDAP1 as a Biological Target on Human Longevity: Integration of Mendelian Randomization, Cohort, and Cell Experiments Validation Study

    Aging cellApr 10, 2025

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