Orco

Gene

2 papers5 findings

Taxon

  • 2 independent labs in 1 country
  • Model organisms2

Effects

4

Egg laying

mediatesin flies1

1 study
  1. Orco mediates egg laying in flies.

    “this response was mediated by olfactory signaling through the odorant receptor co-receptor Orco.”

    Model organismsresponse to yeast odor exposure

    Food perception alone stimulates oviposition through serotonin signaling in Drosophila

    bioRxiv15 Oct 2026Preprint

Lifespan

no changein C. maculatus1

1 study
  1. Orco has no effect on lifespan in C. maculatus.

    “In addition, Orco knockdown extended male lifespan in Population A but had no detectable effect in Population B.”

    Model organismsPopulation B; tested by RNAi-mediated Orco knockdownmales

    Population-dependent effects of Orco on olfactory-guided behavior and lifespan in Callosobruchus maculatus

    Pest management science20 Jul 2026

Antennal electrophysiological activity

upin C. maculatus1

1 study
  1. Orco increases antennal electrophysiological activity in C. maculatus.

    “RNA interference (RNAi)-mediated knockdown of Orco significantly reduced mating-related behavioral responsiveness and antennal electrophysiological activity in both populations, confirming its essential role in olfactory function.”

    Model organismsShown by RNAi-mediated Orco knockdown in Population A and Population Bantenna

    Population-dependent effects of Orco on olfactory-guided behavior and lifespan in Callosobruchus maculatus

    Pest management science20 Jul 2026

Mating-related behavioral responsiveness

is required forin C. maculatus1

1 study
  1. Orco is required for mating-related behavioral responsiveness in C. maculatus.

    “RNA interference (RNAi)-mediated knockdown of Orco significantly reduced mating-related behavioral responsiveness and antennal electrophysiological activity in both populations, confirming its essential role in olfactory function.”

    Model organismsShown by RNAi-mediated Orco knockdown in Population A and Population B

    Population-dependent effects of Orco on olfactory-guided behavior and lifespan in Callosobruchus maculatus

    Pest management science20 Jul 2026

Associations

1

Odor-guided aggregation dynamics

mixedin C. maculatus1

1 study
  1. Orco is associated with odor-guided aggregation dynamics in C. maculatus.

    “Group-level behavioral analyses revealed a significant effect of Orco knockdown on odor-guided aggregation dynamics over time, while no significant effect of population was detected.”

    Model organismsShown by RNAi-mediated Orco knockdown; group-level behavioral analyses

    Population-dependent effects of Orco on olfactory-guided behavior and lifespan in Callosobruchus maculatus

    Pest management science20 Jul 2026

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