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odd-2

Gene

1 paper studies it1 finding

Taxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Institute on Aging and 1 more
  • Model organisms1

Effects

1

Lifespan

downin worms1

1 study

  1. odd-2 shortens lifespan in worms.

    “Knockdown of odd-2 increases lifespan, suppresses the short lifespan of mir-229,64,65,66(nDf63) III mutants, and alters levels of SKN-1 in the ASI neurons.”

    Model organismsshown by knockdown

    The conserved microRNA-229 family controls low-insulin signaling and dietary restriction induced longevity through interactions with SKN-1/NRF2

    Aging cell

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