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nrde-3

Gene

1 paper3 findings

Taxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Institutes of Health and 1 more
  • Model organisms1

Effects

3

Lifespan

downin worms1

1 study

  1. nrde-3 shortens lifespan in worms.

    “also reduced lifespan under the stressful condition of light exposure.”

    Model organismsnrde-3 mutant under light exposure

    Nematode mind: exploring the role of the RNA interference pathway in learning, memory and beyond

    Philosophical transactions of the Royal Society of London. Series B, Biological sciences26 Jun 2025

Positive learning

no changein worms1

1 study

  1. nrde-3 has no effect on positive learning in worms.

    “at the same time, no decline in positive learning was observed.”

    Model organismsnrde-3 mutant

    Nematode mind: exploring the role of the RNA interference pathway in learning, memory and beyond

    Philosophical transactions of the Royal Society of London. Series B, Biological sciences26 Jun 2025

Aversive learning

downin worms1

1 study

  1. nrde-3 impairs aversive learning in worms.

    “nrde-3 mutants exhibited a trend towards deteriorated aversive learning”

    Model organismsnrde-3 mutant

    Nematode mind: exploring the role of the RNA interference pathway in learning, memory and beyond

    Philosophical transactions of the Royal Society of London. Series B, Biological sciences26 Jun 2025

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