Npf
- 1 lab in 1 country
- Funders: Brown University and 4 more
- Model organisms3
Effects
2Neuronal insulin secretion
upin flies1
1 study
Neuronal insulin secretion
upin flies1
Npf increases neuronal insulin secretion in flies.
“loss of gut NPF decreases neuronal insulin secretion”
Model organismsshown by loss of gut NPFbrain
Gut-to-brain regulation of Drosophila aging through neuropeptide F, insulin, and juvenile hormone
Proceedings of the National Academy of Sciences of the United States of America16 Oct 2024
Lifespan
downin flies1
1 study
Lifespan
downin flies1
Npf shortens lifespan in flies.
“Female lifespan is increased when gut NPF is genetically depleted”
Model organismsshown by genetic depletion of gut NPFgutfemales
Gut-to-brain regulation of Drosophila aging through neuropeptide F, insulin, and juvenile hormone
Proceedings of the National Academy of Sciences of the United States of America16 Oct 2024
Latest
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Experiments in model organismsMechanisms
Scientific Reports
Characterization of transcriptomics during aging and genes required for lifespan in Drosophila intestine
Experiments in fliesGut and microbiome