Journal of Genetics and Genomics
Loss of an RNA regulator depletes egg reserves in animals
In an animal experiment, deleting an RNA-processing gene in egg cells caused complete female infertility and progressive depletion of the structures that house developing…In an animal experiment, deleting an RNA-processing gene in egg cells caused complete female infertility and progressive depletion of the structures that house developing eggs.
Animal studyMechanisms
Who was studiedFemale animals with oocyte-specific Srsf2 deletion
What changedAnimals lacking Srsf2 in egg cells progressively lost ovarian follicles, the structures that house developing eggs
The catchSample sizes were omitted, preventing assessment of how many animals supported the follicle-depletion result