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NEU4

Gene

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: China Pharmaceutical University and 3 more
  • Animals1

Effects

2

Kidney fibrosis

upin mice1

1 study

  1. NEU4 increases kidney fibrosis in mice.

    “Conversely, NEU4 overexpression exacerbates the progression of renal fibrosis.”

    Animalsspecifically in the kidneykidneymales

    Targeting Neuraminidase 4 Attenuates Kidney Fibrosis in Mice

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)Aug 13, 2024

More on Kidney fibrosis

Cellular senescence

upin mice1

1 study

  1. NEU4 increases cellular senescence in mice.

    “NEU4 knockdown specifically in the kidney attenuates the epithelial-to-mesenchymal transition, reduces the production of pro-fibrotic cytokines, and decreases cellular senescence in male mice.”

    Animalsspecifically in the kidneykidneymales

    Targeting Neuraminidase 4 Attenuates Kidney Fibrosis in Mice

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)Aug 13, 2024

More on Cellular senescence

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