There is 1 paper on Mup1activity in aging research: none in people yet, 1 in cells.
See all 1 papers on Mup1activity
At a glance
The findings reach worms or flies, none yet in people. 1 lab in 1 country.
None of its findings points the other way.
Worms or flies: a single group. Cells, mice and humans: nothing yet.
- 1 lab in 1 country
- Funders: National Cancer Institute and 3 more
- Cells1
Interventions
1Myriocin
downin yeast cells1
1 study
Myriocin
downin yeast cells1
Myriocin inhibits Mup1activity in drug-treated cells.
“newly synthesized Mup1 traffics to the plasma membrane and is stable for several hours but is inactive in drug-treated cells”
Cellsin drug-treated cells
Enhancing lifespan of budding yeast by pharmacological lowering of amino acid pools
Aging
Upstream
1Sphingolipids
is required forin yeast cells1
1 study
Sphingolipids
is required forin yeast cells1
sphingolipids are required for Mup1activity in yeast cells (shown by phytosphingosine rescue in myriocin-treated cells).
“thus confirming a sphingolipid requirement for Mup1 activity”
Cellsshown by phytosphingosine rescue in myriocin-treated cells
Enhancing lifespan of budding yeast by pharmacological lowering of amino acid pools
Aging