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MIR548AZ

Gene

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Jinan Science and Technology Bureau and 2 more
  • Humans1

Effects

3

Cell cycle regulation

downin human cells1

1 study

  1. MIR548AZ inhibits cell cycle regulation in human cells.

    “inhibited cell proliferation by cyclin D1 and cyclin-dependent kinase 6 (CDK6)”

    Cellsupregulation in hAECshuman amniotic epithelial cells

    miR-548az-5p induces amniotic epithelial cell senescence by regulating KATNAL1 expression in labor

    Scientific reports5 Dec 2024

More on Cell cycle regulation

Senescence-associated secretory phenotype (SASP)

upin human cells1

1 study

  1. MIR548AZ induces senescence-associated secretory phenotype (SASP) in human cells.

    “the upregulation of miR-548az-5p suppressed KATNAL1 expression, disorganized microtubules, increased senescence-associated secretory phenotype-related biomarkers”

    Cellsupregulation in hAECshuman amniotic epithelial cells

    miR-548az-5p induces amniotic epithelial cell senescence by regulating KATNAL1 expression in labor

    Scientific reports5 Dec 2024

More on Senescence-associated secretory phenotype (SASP)

KATNAL1

downin human cells1

1 study

  1. MIR548AZ inhibits KATNAL1 in human cells.

    “the upregulation of miR-548az-5p suppressed KATNAL1 expression”

    Cellsupregulation in hAECshuman amniotic epithelial cells

    miR-548az-5p induces amniotic epithelial cell senescence by regulating KATNAL1 expression in labor

    Scientific reports5 Dec 2024

More on KATNAL1

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