There are 5 papers on MIR26B in aging research: 1 observational study in people, 3 in animals, 1 in cells.
At a glance
The findings reach mice, none yet in people. 2 independent labs in 1 country.
None of its findings points the other way.
- 2 independent labs in 1 country
- Funders: National Natural Science Foundation of China and 1 more
- Humans1
- Animals3
- Cells1
Effects
3ASPN
downin mice1
1 study
ASPN
downin mice1
MIR26B inhibits ASPN in chondrocytes.
“asporin can be inhibited by miR-26b-5p”
Animalsin chondrocytescartilage
Rheumatology (Oxford, England)
ESR1
downin human cells1
1 study
ESR1
downin human cells1
MIR26B inhibits ESR1 in human cells.
“miR-26b-3p suppresses estrogen receptor 1 (ESR1) expression by directly binding to the coding sequence (CDS) region of its message RNA (mRNA)”
Cellsmesenchymal stem cell
Stem cells and development
Cell proliferation
downin human cells1
1 study
Cell proliferation
downin human cells1
MIR26B inhibits cell proliferation in human cells (overexpression).
“The overexpression of miR-26b-3p greatly inhibited the proliferation of hUC-MSC in vitro”
Cellsoverexpressionmesenchymal stem cell
Stem cells and development
Upstream
1Serial passage
upin human cells1
1 study
Serial passage
upin human cells1
serial passage increases MIR26B in human cells during serial in vitro passage.
“miR-26b-3p was significantly upregulated during serial in vitro passage of hUC-MSC”
Cellsduring serial in vitro passagemesenchymal stem cell
Stem cells and development