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MIR138-1

Gene

2 papers study it2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: China Postdoctoral Science Foundation and 5 more
  • Animals2

Effects

1

Bone loss

upin mice1

1 study

  1. MIR138-1 increases bone loss in mice.

    “led to worse bone loss in aged osteoblastic miR-138-5p transgenic mice in vivo”

    Animals

    MiR-138-5p Targets MACF1 to Aggravate Aging-related Bone Loss

    International journal of biological sciencesJul 18, 2022

Associations

1

Bone mineral density

downin humans1

1 study

  1. MIR138-1 is associated with bone mineral density in humans.

    “miR-138-5p level was found to be negatively correlated with BMD”

    Humansin bone specimens of senile osteoporotic patientsbone

    MiR-138-5p Targets MACF1 to Aggravate Aging-related Bone Loss

    International journal of biological sciencesJul 18, 2022

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