AgingResearch.NewsJoin free

MIR1204

Gene

1 paper2 findings

HGNCNCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Basic and Applied Basic Research Foundation of Guangdong Province and 4 more
  • Humans1

Effects

2

Aortic aneurysm and dissection

upin mice1

1 study

  1. MIR1204 increases aortic aneurysm and dissection in mice.

    “miR-1204 aggravates angiotensin II-induced AAD formation, and inhibition of miR-1204 attenuates β-aminopropionitrile monofumarate-induced AAD development in mice.”

    Animalsangiotensin II-induced model; also supported by miR-1204 inhibition in the β-aminopropionitrile monofumarate-induced modelaorta

    Aging aggravates aortic aneurysm and dissection via miR-1204-MYLK signaling axis in mice

    Nature communications16 Jul 2024

More on Aortic aneurysm and dissection

Cellular senescence

upin cells1

1 study

  1. MIR1204 induces cellular senescence in cells.

    “miR-1204 induces vascular smooth muscle cell (VSMC) senescence to form a positive feedback loop.”

    Cellsvascular smooth muscle cell

    Aging aggravates aortic aneurysm and dissection via miR-1204-MYLK signaling axis in mice

    Nature communications16 Jul 2024

More on Cellular senescence

Latest

Related