MIR-495
1 paper studies it4 findings
None of its findings points the other way.
- 1 lab in 1 country
- Animals1
Effects
4TGF-β signaling
downin mice1
1 study
TGF-β signaling
downin mice1
MIR-495 inhibits TGF-β signaling in mice.
“inactivating the Myostatin/TGF-β/Smad3 signaling pathway”
Animalsenforced expression
Archives of biochemistry and biophysics
Peak tetanic tension
upin mice1
1 study
Peak tetanic tension
upin mice1
MIR-495 improves peak tetanic tension in mice.
“Enforced miR-495 expression could intensively strengthen the muscle mass, in situ muscular electrophysiological indexes, including peak tetanic tension (Po) and peak twitch tension (Pt)”
Animalsenforced expression
Archives of biochemistry and biophysics
Muscle mass
upin mice1
1 study
Muscle mass
upin mice1
MIR-495 increases muscle mass in mice.
“Enforced miR-495 expression could intensively strengthen the muscle mass”
Animalsenforced expression
Archives of biochemistry and biophysics
Stem cell differentiation
upin mouse cells1
1 study
Stem cell differentiation
upin mouse cells1
MIR-495 increases stem cell differentiation in mouse cells.
“Enforced miR-495 expression by its mimic could enormously facilitate the differentiation and regeneration of both mouse myoblast C2C12 cells and muscle satellite cells.”
Cellsenforced expression
Archives of biochemistry and biophysics
Latest
Archives of Biochemistry and Biophysics
MiR-495 reverses in the mechanical unloading, random rotating and aging induced muscle atrophy via targeting MyoD and inactivating the Myostatin/TGF-β/Smad3 axis
Experiments in miceMuscle atrophy