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Minos1b

Gene

1 paper2 findings

Taxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Deutsche Forschungsgemeinschaft and 2 more
  • Model organisms1

Effects

2

Elongated filament formation

upin flies1

1 study

  1. Minos1b induces elongated filament formation in flies.

    “DmMIC10b exhibits the unique ability to polymerize into elongated filaments upon overexpression.”

    Model organismsupon overexpression

    The Drosophila MIC10 orthologue has a propensity to polymerize into cristae-shaping filaments

    bioRxiv (Cold Spring Harbor Laboratory)17 Apr 2023Preprint

Mitochondrial cristae architecture

upin flies1

1 study

  1. Minos1b improves mitochondrial cristae architecture in flies.

    “Loss of DmMIC10b disturbs cristae architecture of mitochondria and reduces the life-span and fertility of flies.”

    Model organismsshown by loss of DmMIC10b

    The Drosophila MIC10 orthologue has a propensity to polymerize into cristae-shaping filaments

    bioRxiv (Cold Spring Harbor Laboratory)17 Apr 2023Preprint

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