LUC7L3
1 paper2 findings
- 1 lab in 1 country
- Funders: Fundamental Research Funds for the Central Universities and 2 more
- Cells1
Effects
1Cellular senescence
downin human cells1
1 study
Cellular senescence
downin human cells1
LUC7L3 prevents cellular senescence in human cells.
“LUC7L3 depletion impairs cell proliferation compared to the other Luc7p paralogs, resulting in cell apoptosis and senescence.”
Cellsshown by knockdown or depletion
LUC7L3 is a downstream factor of SRSF1 and prevents genomic instability
Cell insightMar 23, 2024
Upstream
1SRSF1
upin human cells1
1 study
SRSF1
upin human cells1
SRSF1 increases LUC7L3 in human cells.
“identified SRSF1 as an upper stream regulator of LUC7L3, promoting the translation of LUC7L3 protein.”
Cells
LUC7L3 is a downstream factor of SRSF1 and prevents genomic instability
Cell insightMar 23, 2024
Latest
Cell Insight
LUC7L3 is a downstream factor of SRSF1 and prevents genomic instability
Experiments in human cellsDNA damage response