What does the research say about LPLRS15285?

LPLRS15285

There is 1 paper on LPLRS15285 in aging research: 1 observational study in people. The newest story, Nov 9, 2026: “Clinical obesity has genetic links beyond body mass index”.

Gene

1 paper studies it4 findings

1 new paper in 30 daysSee all 1 papers on LPLRS15285

At a glance

The findings reach people, from one lab or study. 1 lab in 1 country.

“Carriers of rs15285 had significant differences in cardiovascular risk factors (increased triglyceride and decreased high-density lipoprotein cholesterol)”

Genome-Wide Analysis of Clinical Obesity Identifies Lipoprotein Lipase Variants Discordant from BMI That Increase Cardiovascular RiskAHA Scientific Sessions 2026 abstract2026doi:10.1161/circ.154.suppl_1.8753

None of its findings points the other way.

1 lab in 1 country

Humans1

Associations

Coronary artery disease

upin humans1OR 1.048–1.069

1 study

LPLRS15285 is associated with coronary artery disease in humans (rs15285 carriers in independent cohorts) (Beta: 0.052; OR: 1.048-1.069).
“In independent cohorts, rs15285 carriers had significantly elevated risk for coronary artery disease (Beta: 0.052; OR: 1.048-1.069).”
Humansrs15285 carriers in independent cohorts
Clinical obesity has genetic links beyond body mass index
AHA Scientific Sessions 2026 abstractNov 2, 2026

Latest

1 paper in 12 months

AHA Scientific Sessions 2026 AbstractNov 9

Clinical obesity has genetic links beyond body mass index

Of 127 genetic regions linked to clinical obesity, 63 had no significant link to body mass index in an analysis across five ancestry groups.Of 127 genetic regions linked to clinical obesity, 63 had no significant link to body mass index in an analysis across five ancestry groups.

Genetic association studyMechanisms

Paper