There is 1 paper on LManII in aging research: none in people yet, 1 in animals.
At a glance
The findings reach worms or flies, none yet in people. 1 lab in 2 countries.
None of its findings points the other way.
Worms or flies: a single group. Cells, mice and humans: nothing yet.
- 1 lab in 2 countries
- Funders: Bundesministerium für Forschung, Technologie und Raumfahrt and 4 more
- Model organisms1
Effects
2Autophagy
upin flies1
1 study
Autophagy
upin flies1
LManII increases autophagy in flies (gut-specific overexpression).
“gut-specific overexpression of a lysosomal mannosidase increased autophagy, gut homeostasis, and lifespan”
Model organismsgut-specific overexpressionintestine
eLife
Lifespan
upin flies1
1 study
Lifespan
upin flies1
LManII extends lifespan in flies (gut-specific overexpression).
“gut-specific overexpression of a lysosomal mannosidase increased autophagy, gut homeostasis, and lifespan”
Model organismsgut-specific overexpressionintestine
eLife